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MethMotif Updates



Current release ► MethMotif version 2.0 Program updates:
TF cards were updated with a TF cofactor list that
includes:
1) TF logos and binding site methylation profiles in the
context of each TF partners;
2) Genomic locations of the TF of interest in the context
of each TF partners;
3) Gene ontology analyses of TF's targets in the context
of each TF partners.
24 June 2020
MethMotif version 2.0 Data updates:
1) MethMotif plant database was added;
2) 23 new factors in plant species Arabidopsis thaliana
were added.
24 June 2020
MethMotif version 1.3 Program updates:
MethMotif has been additionally hosted in Compute Canada
server via https://methmotif.org.
5 March 2020
MethMotif version 1.3 Program updates:
MethMotif API - TFregulomeR has been launched.
5 November 2019
MethMotif version 1.3 Data updates:
1) 18 new DNA binding proteins in GM12878 cell line
were added (details).
2) 2 new DNA binding proteins in H1-hESC cell line
were added (details).
3) 3 new DNA binding proteins in HCT116 cell line
were added (details).
4) 4 new DNA binding proteins in HEK293T cell line
were added (details).
5) 9 new DNA binding proteins in HeLa-S3 cell line
were added (details).
6) 89 new DNA binding proteins in HepG2 cell line
were added (details).
7) 39 new DNA binding proteins in K562 cell line
were added (details).
8) 25 new DNA binding proteins in MCF-7 cell line
were added (details).
15 March 2019
MethMotif version 1.3 Data updates:
1) 16 new DNA binding proteins in LNCaP, a prostate
adenocarcinoma cell line, were added (details).
6 March 2019
MethMotif version 1.3 Data updates:
1) 13 new DNA binding proteins in HEK293 cell line
were added (details).
2) 9 new DNA binding proteins in H9 cell line
were added (details).
3) 18 new DNA binding proteins in HUES64 cell line
were added (details).
2 January 2019
MethMotif version 1.3 Data updates:
17 new DNA binding proteins in HEK293T cell line
were added (details).
28 November 2018
MethMotif version 1.3 Bug fixed:
Malfunction of search engine autocompletion in
https has been fixed.
17 November 2018
MethMotif version 1.3 Data updates:
2 new factors were added in human SNU398 cell line
(details).
6 November 2018
MethMotif version 1.3 Data updates:
1) MethMotif mouse database was added;
2) 39 new factors in mouse MEL cell line were added
(details).
4 November 2018
MethMotif version 1.2 Program updates:
CAPTCHA was added in MethMotif Batch Query to
avoid overloading by robots.
22 October 2018
MethMotif version 1.2 Program updates:
1) A link to MethMotif card was added in MethMotif
Batch Query outputs;
2) Three states of MethMotif logo based on DNA
methylation levels were added;
3) A more explicit MethMotif logo legend was added;
4) Motif distrubition was added for each TFBS.
1 October 2018
MethMotif version 1.1 Data updates:
1) 11 new factors were added for GM12878;
2) 22 new factors were added for MCF-7;
3) 1 new factors were added for H1-hESC;
4) 2 new factors were added for HCT116;
5) No new release for HeLa-S3 in ENCODE.
19 April 2018
MethMotif version 1.1 Data updates:
32 new factors were added for HepG2.
13 April 2018
MethMotif version 1.1 Data updates:
65 new factors were added for K562.
9 April 2018
MethMotif version 1.1 Data updates:
Data for IMR-90, SK-N-SH and A549 were added.
3 April 2018
MethMotif version 1.1 Data updates:
Data for K562, GM12878, HepG2, H1-hESC, MCF-7,
HCT116, HeLa-S3 and HEK293 were added.
26 March 2018



ChIP-seq datasets in MethMotif

Species Number of ChIP-seq experiments Source Download date
Arabidopsis thaliana 74 GEO and GTRD 14 Feb 2020

Whole genome bisulfite sequencing datasets in MethMotif

Species Number of WGBS experiments Source Release date
Arabidopsis thaliana 10 GEO 14 Feb 2020