Homepage Motif Database


MethMotif is a collaborative academic TFBS database hosted at the Digital Research Alliance of Canada, maintained by the Memorial University of Newfoundland, and involving investigators from the Cancer Science Institute of Singapore and the École normale supérieure (Paris).

If you currently use MethMotif, please cite us as follows:

Quy Xiao Xuan Lin, Stephanie Sian, Omer An, Denis Thieffry, Sudhakar Jha and Touati Benoukraf. (2018) MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles. Nucleic Acids Res., 10.1093/nar/gky1005. [Manuscript]

A manuscript describing MethMotif API - TFregulomeR has been published. If you currently use TFregulomeR, please cite us as follows:

Quy Xiao Xuan Lin, Denis Thieffry, Sudhakar Jha, Touati Benoukraf. (2019) TFregulomeR reveals transcription factors’ context-specific features and functions. Nucleic Acids Res., 10.1093/nar/gkz1088. [Manuscript]

A manuscript describing new MethMotif functionalities has been submitted. The preprint version is available here:

Dyer M, Lin QXX, Shapoval S, Thieffry D, Benoukraf T. MethMotif.org 2023: The transcription factor binding motifs database that integrates cell-specific functions, co-factors and DNA methylation profiles. Research Square; 2022. DOI: 10.21203/rs.3.rs-2253164/v1. [Manuscript]

Current contributors: Matthew Dyer: Memorial University of Newfoundland; Aida Ghayour-Khiavi: Memorial University of Newfoundland; Denis Thieffry: École normale supérieure (Paris); Touati Benoukraf: Memorial University of Newfoundland; Contact: tbenoukraf@mun.ca.